Are you feeling more cold than others? You could be micro nutrient deficient

Vitamins and minerals are essential to a myriad of physiologic functions, and a defficiency results in a wide variety of disorders. Among these disorders one of them is the inability of mammals to maintain body temperature adequately in cold. A study has been seen/published that Iron-deficient humans are unable to maintain their body temperature during exposure to cold.

Cold Associated Anaemia

Iron deficiency may exert its effects on body temperature through two distinct, yet related, mechanisms, one involving anaemia and the other involving tissue iron deficiency. Iron-deficiency anaemia results in decreased oxygen transport from the lungs to tissues, and this reduction in oxygen availability inhibits physiological responses to cold, including peripheral vasoconstriction, a heat- conserving process, and increased metabolic rate, a heat-generating process. The inability to conserve and produce body heat properly accounts for hypoxia-induced hypothermia (Low Body Temperature). Hypoxia, created by reducing the oxygen content or the pressure of inspired air, results in hypothermia Iron-deficient anaemic patients rapidly become hypothermic when placed in a cold environment (39°F [4°C]), However correcting their anaemia by supplementing and restoring micronutrients results in better thermoregulation.

As per recent research of NCBI by John L. Beard on Micronutrient Deficiency States and Thermoregulation in the Cold, the deficiency of iron can be circumvented by Colocasia Arabica which is one of the richest source of Iron due to its erthyropoetic stimulatory action, along with Colocasia, Withania Somnifera increases RBC production by acting on bone marrow. It has also been studied that several micronutrients like Zinc, Copper, etc. are vital in the process of thermoregulation in the human body. Nature is considered as an ever giving fountain of wealth in terms of nutritive value encapsulated in its herbs. For eg. Helianthus Annuus is a rich source of Zinc, Selenium, magnesium which increases the inter cellular metabolism and hence produces heat. Another herb linum usitatissimum supplements alpha- linoleicacid, a form of fat, which acts as natural insulator for the human body.

An increase in blood circulation also regulates the body temperature with vitamin B complex has been shown to increase the blood circulation. Various herbs such as wheat bran are a treasure of vitamin content & supplements Vitamin B6, thiamine to keep the engine of heat running.

A blend of all these herbs along with 29 herbs is available with a brand named Amyron. A phytomineral bone therapy which can play a vital role in the thermoregulation in the cold by increasing the Haemoglobin level and providing micronutrients, with this warmth from mother nature, winter will be less cold.

Exploring the new avenues in management of Rheumatoid Vasculitis

Rheumatoid vasculitis is a condition that causes blood vessels to be inflamed. It happens in some people who have had rheumatoid arthritis (RA) for a long time. RA affects millions of people. It happens most often in women in their 40s to 60s.

RA is an autoimmune disease. RA usually first affects joints. If it also affects blood vessels, it leads to rheumatoid vasculitis. Rheumatoid vasculitis can affect both small and medium-sized blood vessels. It doesn’t affect large blood vessels, except in rare cases. Damage to blood vessels may cause blockage of blood vessels causing minimum or no supply of oxygen to cells and tissues leading to tissue death.

Rheumatoid vasculitis: Causes and risks

Due to the complexity of the immune system, researchers have not totally understood the causes. According to hypothesis, a combination of various factors in which genes play an important role lead to rheumatoid vasculitis.  As far as risk is concerned, all RA patients  fall in the same category except smokers whose risk  increases by many folds.

Signs & Symptoms of rheumatoid vasculitis

Symptoms often don’t start until several years after someone have had RA for about 10 years or more. They often start after a period when the joint disease has become less active.

Rheumatoid vasculitis can affect blood vessels in many parts of the body. For this reason, it can cause many different symptoms. It most often damages blood vessels to the skin, fingers and toes, nerves, eyes, and heart. This reduces blood flow to these areas and damages them.

Many people with rheumatoid vasculitis have general symptoms, such as tiredness, fever, and weight loss. These symptoms are common in RA as well but their severity increases in rheumatoid vasculitis condition. Other symptoms of rheumatoid vasculitis may include:

  • Skin sores (ulcers)
  • Purplish bruises
  • Pain in fingers and toes
  • Tissue death (gangrene) in fingers and toes
  • Muscle weakness in parts of the body
  • Loss of feeling in parts of the body
  • Tingling and pain in parts of the body
  • Pain in eyes
  • Redness in eyes
  • Blurry vision
  • Chest pain
  • Abnormal heart rhythms, some of which may be fatal

Diagnosis and Management of rheumatoid vasculitis

Various tests are conducted to check inflammation, infections along with this biopsy of the affected blood vessel is also done to assess the damage of the tissue. Management may vary depending on how severe the vasculitis is and which blood vessels are affected. There is no established treatment for rheumatoid vasculitis. But early measures can help control vessel damage and ease symptoms. The management regime also includes:

  • Steroid   medicines   given   by   mouth   or   through   a   vein   to   reduce inflammation
  • Immunosuppressant medicines such as rituximab to help control the immune system
  • Other immunosuppressant medicines such as cyclophosphamide, if the vasculitis is severe

These drug possess the risk of bleeding in urinary bladder or increased risk of infection. Patients are often prescribed with Vitamin – D and calcium supplements to ward off adverse effects like bone resorption. 

New approach in management of rheumatoid vasculitis

In Ayurveda RA is conceptually very well correlated with Aamvata. It is classified as a joint disorder which is further classified into (1) Cestavanta (Mobile) and (2) Sthira (Non-mobile). It is a Krichasadhaya Vyadhi but in modern system of medicine it’s an autoimmune disease as well as a metabolic disorder because of involvement of Aama which is an intermediated product formed during abnormal metabolism of food.

During the examination of joints this information is critical because disease like Sandhivata always occur in Cala sandhis but not in Sthira sandhi, because of predominance of Vata in Cala sandhi. Absence of Slesmadhara kala in which Slesaka kapha is absent or slightly present. This is an important diagnostic features that Amavata condition prevail in Slesaka kapha sandhi (synovial joints) only. That means Amavata affects the joints in limbs, mandible and vertebrae only.

The effective management strategies of this disease is mentioned in various Ayurveda texts. One such management approach is the use of Rasonadi Kwath which is mentioned in 26th chapter of Bhavprakash. Rasonadi Kwath contains Rasona, Shunthi and Nirgundi. The combination of these drugs is Katu pradhan tikta rasa and except Amla rasa all others rasas are present in small amounts. It is Pradhanataha Ruksha and Teekshna in Guna, Ushana veerya, Pradhanatah Katu Vipaka, Kapha- Vatahara and Deepana.

Kwath is Laghu to digest as compared to Swarasa and Kalka. Rasonadi kwath is Karshaka in nature. It acts against the Snigdha, Pichila pradhana Gunas of Ama, and it reduces the Sarrvadaihika Ama lakshanas which are nothing but Samanya lakshana of Amavata.

Other Herbs that reduce inflammation may help downregulate the autoimmune response. Several herbs that have been traditionally used for this purpose also have been investigated scientifically to determine their mechanism(s) of action. These herbs include: Hops, Artemisia annua, Sarsaparilla, Reishi Mushroom, Ashwagandha, Nettle, Rehmannia, and Chinese Skullcap (Scute). Other important herbs that may have a role in decreasing both inflammation and the overzealous auto immune response include Boswellia serrata, Green Tea, Ginger, Turmeric, White Willow, Stephania and Chinese Thunder God Vine. One such herb Rehmannia (Rehmannia glutinosa) is also mentioned in Chinese tradional medicine text and has shown promise in bringing balance to aggressive autoimmune states. It is also used as blood and kidney (adrenal) tonic. Studies have shown that this herb possesses both immune-enhancing and immune-suppressant effects. This dual activity may render Rehmannia glutinosa superior to Disease Modifying Anti-Rheumatic Drugs (DMARDs), which can suppress the immune system to an extent that susceptibility to opportunistic infections is increased.

Modern pharmacological research has isolated various components in Rehmannia, which may be responsible for its adrenal toning, immuno- modulatory, and anti-inflammatory effects. Rehmannia also reduces allergic reactions by decreasing histamine release caused by TNF-alpha activity on mast cells. Another such herb is Boswellia (Boswellia serrata) which is a tree gum extract that has been shown to inhibit Th1 cytokines and promotes Th2 cytokines, which helps to reverse the imbalance of Th1 and Th2 that increases inflammation. Ginger (Zingiber officinale) has been shown to inhibit cyclooxygenase (COX) and lipoxygenase pathways. Ginger’s high concentration of proteolytic enzymes (zingibain) are partially responsible for its ability to subdue pain and inflammation. Proteolytic enzymes block the action of several inflammatory substances, including prostaglandins and leukotrienes. Ginger has been shown to decrease pain in arthritis. Turmeric (Curcuma longa) is a bright yellow herb with powerful anti-inflammatory properties, which are credited to a chemical component, curcumin. Research suggests that Turmeric suppresses NFkB and interleukin-8, while enhancing glutathione biosynthesis. Turmeric also inhibits NFkB activation.

Ayurvedic practitioners consider that disease is due to lack of balance within the body systems. Establishing proper balance by employing the above botanicals, therapies, and lifestyle modifications may thus offer a safe and effective alternative to conventional treatment and bring new hope to patients suffering from autoimmune diseases and their complications such as rheumatoid vasculitis.

Hair Strengthening Herbs

The word "hair" usually refers to two distinct structures. The part beneath the skin, called the hair follicle, or, when pulled from the skin, the bulb. This organ is located in the dermis and maintains stem cells, which not only re-grow the hair after it falls out, but also are recruited to regrow skin after a wound; and the shaft, which is the hard filamentous part that extends above the skin surface. Hair loss is a common concern for many men and women. There are many reasons your hair may fall out, from genetics and vitamin deficiencies, to hormone changes. Some medical conditions, such as thyroid disease, may also cause hair to thin or fall out. There is no magic bullet for growing hair, but research has shown some herbs may slow hair loss or help promote new growth. Herbs rely on the natural components stored inside to promote healthy hair and scalp, rather than the synthetic ingredients and chemicals that can damage hair and cause build-up. Hence fore herbs and herbal infusions have been used for centuries to naturally soften hair, increase manageability, and restore luster, body, and bounce of hairs. Some of the herbs which have frequently been used for making hairs healthy and strengthening them are given bellow.

Aloe, (Aloe vera Tourn. Ex L.). Aloe makes hair more manageable, smoother, silkier, and healthier. Aloe conditions, moisturizes and creates a smooth shine. The gel of the plant can restore the pH balance of the scalp which helps to encourage growth. It is also a great way to moisturize the scalp since it is super hydrating. Gel can apply directly to the scalp and massage for the best results or create an Aloe rinse. The International Journal of Pharm. Tech. Research reports that Aloe vera "gel is used traditionally for hair loss and for improvement in hair growth following alopecia."

Amla (Phyllanthus emblica L.). Amla also known as the Indian Gooseberry, is an excellent hair conditioning herb, provides nourishment that penetrates the scalp and strengthens hair at its root to promote stronger, healthier new growth and helps with hair loss by normalizing blood supply and good for hair loss and thinning. Amla has been used as a hair tonic in traditional recipes for enriching hair growth and pigmentation. A fixed oil, obtained from Amla, is used to strengthen and promote hair growth. The dried fruit, which improves hair hygiene, has long been utilized as an important ingredient of shampoo and hair oil. Vitamins A and C present in Amla help prevent hair loss and dandruff as well.

Aritha or Reetha, (Sapindus mukorrosi Gaertn.). Reetha also known as Soapnuts, is an excellent hair tonic, long known for its benefits for healthy hair and scalp. Used for centuries as an anti-hair loss shampoo, the natural antifungal, and antibacterial properties may help with dandruff. It cleanses the skin of oily secretion and is even used as a cleanser for washing hair as it forms a rich natural lather because of the presence of saponin. The natural saponins not only cleanse hair, they add body and sheen and make hair feel thicker, silky and smooth.

Bhringraj (Eclipta alba (L.) Hassk.) Bhringraj is an ancient Ayurvedic herbal remedy for hair loss, premature greying and skin allergies, which helps rejuvenate skin and hair. Considered the "king of herbs" for hair growth, it  adds deep moisture and acts like a multivitamin for hair to help strengthen the hair shaft, provide natural shine and may also help with dandruff. Recent research findings suggest that methanol extract of Eclipta alba may have potential as a hair growth promoter.

Mehdi / Henna (Lawsonia inermis L.). The powdered leaves of mehdi have been used since ancient times as a natural dye. Henna gives hair a reddish tint and, when mixed with other botanicals such as indigo and cassia, can create a variety of beautiful warm colours. Henna, a deep conditioner, coats the hair shaft, seals in moisture, tightens the cuticle, increases body and lustre and makes hair silky soft.

Shikakai (Acacia concinna DC.). Shikakai is referred to as "fruit for the hair." It has a naturally mild pH, and it gently cleans hair and increases bounciness and silkiness of hair without stripping it of natural oils. As a natural hair conditioner, Shikakai is said to promote hair growth, strengthen hair roots and clear dandruff.

Rosemary (Rosemarinus officinalis L. ), Rosemary encourages hair growth by improving blood flow to the scalp, encourages strong, healthy hair, stimulates growth, increases manageability and adds shine. The stimulating and revitalizing properties of Rosemary help condition both hair and scalp. It has the added bonus of stopping premature greying of hairs as well. It is also super moisturizing so it can be used to treat a dry, flaky scalp which may stand in the way of new growth occurring. One study published in Phototherapy Research Journal found that the topical use of Rosemary on mice showed an improvement in hair growth by blocking excess testosterone production. 

Stinging Nettle (Urtica dioica L.): Stinging Nettle also known as Bichhu Booti, helps block the over production of dihydrotestosterone (DHT) which leads to hair loss. While it may not create new growth, it does stop hair loss while helping to restore balance to the hormones that create hair growth. It also has strong antibacterial properties stimulates the scalp, improves circulation, and helps promote fuller, more radiant hair. Bichhu Booti has a long-standing reputation for preventing hair loss and making the hair soft and shiny. Stinging Nettle, an excellent hair conditioner, and rich in minerals and plant hormones, is tonic and astringent and gives a healthy gloss to hair. Stinging Nettle is said to be a remedy for oily hair, dandruff, and hair shaft breakage. A study, published in Phytomedicine and Therapeutics Journal to determine this aspect of Stinging Nettle, found that this result, "may be attributed to the presence of agglutinin, a lectin, and other active compounds in the plant."

Lavender (Lavandula officinalis Chaix ). Lavender has anti-inflammatory, anti- bacterial, anti-fungal and antiseptic properties that help with hair loss, shedding and inflammatory scalp conditions. Its ability to balance oil production makes it a great hair care herb for all hair types. This popular herb has antibacterial properties so it will leave the scalp free of anything getting in the way of generating growth. If your scalp has a lot of parasites, fungus, or other less than desirable things, it will be almost impossible for growth to take place. This herb is commonly used as a topical in the form of oil, but can also be made into a tea. According to University of Maryland Medical Center, "In one study of 86 people with alopecia areata (an autoimmune disease that causes hair to fall out, often in patches), those who massaged their scalps with lavender and other essential oils daily for 7 months experienced significant hair regrowth compared to those who massaged their scalps without the essential oils.

Yashtimadhu / Licorice Root( Glycyrrhiza glabra L.). Yashtimadhu is a traditional herbal remedy used in India and around the world. The root is good for improving hair growth and is often used in products to help with hair loss. It helps keep the scalp moist and hydrated and helps strengthen the hair shaft. Recent scientific research showed that hydro-alcoholic extract of liquorice has good hair growth promoting activity. Therefore, it has been suggested that liquorice can be safely used in herbal formulations in treatment of various types of Alopecia.

Green Tea (Camellia sinensis (L.) O. Kuntze). Green tea has antioxidants which benefit the hair and scalp by decreasing hair loss and soothing hair conditions like dandruff and psoriasis. It contains natural vitamin C which helps guards against damage from UV rays; vitamin E which helps dry or damaged hair; and panthenol, also known as vitamin B-5, which helps strengthen and soften hair and prevents split ends.

Marua /Basil (Ocimum basilicum L.). Marua stimulates hair follicles; increases scalp circulation and promote hair growth. The magnesium in basil helps protect hair from breakage, and its anti-inflammatory properties help soothe the roots. Basil adds lustre to dull hair.

Tulsi/holy basil (Ocimum tenuiflorum L.). Tulsi or Holy Basil, is helpful in conditioning the scalp by improving blood circulation, thereby helping cells receive the nutrients and oxygen. It is also useful for dandruff and general hair care.

Burdock (Arctium lappa L.). Burdock strengthens hair follicles, to promote healthy hair growth and improve the overall condition of hair. The presence of silica, essential fatty acids and phytosterols in burdock help soothe irritated scalp conditions like dandruff, decrease breakage and repair hair while adding sheen, hydration, lustre and help generate new growth. The mucilage in Burdock root also helps add “slip” to your hair to make detangling easier. In fact, the fatty acids in this plant can even be used to treat psoriasis.

Calendula, (Calendula officinal L.). Calendula soothing to sensitive scalps, is rich in plant minerals that protect the hair from free radicals, and the scalp from bacterial growth. A calendula hair rinse conditions, adds shine and can be used to create warm highlights.

Cassia (Cassia obtusa Roxb.). Cassia often called neutral henna, is not a henna at all. It possesses anti-bacterial, anti-fungal, and moisture retention properties and is an excellent conditioner. The leaves look like henna but contain a golden yellow dye molecule that adds colour to very pale blond or gray hair. As an excellent conditioner, it strengthens the hair shaft, enhances volume, adds shine and may help improve dandruff. It is often mixed with true henna makes hair black.

Chamomila (Matricaria chamomilla L ). Chamomila is used to soothe the scalp and condition hair. It adds highlights to fair hair and sheen to dark hair and it conditions and softens. Chamomila tea makes a fantastic hair rinse for blonds, strengthens scalp tissues, and promotes healthy hair growth by correcting issues with scalp inflammation.

Methi/Fenugreek (Trigonella foenum-graecum L. ). Methi provides natural proteins for the nourishment and health of hair, stimulates blood flow to the root of the hair, and was used to combat hair loss. Used as a treatment for dandruff, thinning hair, and damaged hair, it is said to preserve hair's natural color and keep hair silky.

Alsi / Flaxseed (Linum usitatissimum L.) Alsi is rich in mucilage, a complex mixture of polysaccharides that form a soothing gelatinous substance when water is added. The mucilage provides slip like a conditioner that helps detangle hair. Alsi, very rich in Omega-3 essential fatty acids, strengthens the hair shaft and may help with hair loss.

Adarak /Ginger (Zingiber officinale Rosc.). Adarak is a powerful antifungal agent that is used in shampoo to treat dandruff. It helps increase scalp circulation which stimulates hair follicles and encourages growth. The fatty acids composition of ginger root is great for thinning hair. Ginger also has antiseptic properties that work to help with dandruff.

Patwa/Javakusuma (Hibiscus sabdariffa L.). Patwa is used to lessen gray hair and promote hair growth. The flowers and leaves contain mucilage and plant proteins that help in the treatment of dandruff and hair loss. Patsan infusions are great as a final herbal rinse, add warm red hues, provide excellent slip and help detangle naturally curly hair.

Hops (Humulus lupulus L. ). Hops help heal and repair damaged hair. They contain nourishing oil that is an effective hair conditioner and thickener. Hops help stimulate scalp circulation and encourage growth. Its antiseptic properties help with dandruff.

Neel/Indigo, (Indigofera tinctoria Retz.). Neel leaves are harvested, dried, and ground into a powder that contains a deep blue dye used for centuries in textiles, arts, and as a natural jet black hair colorant. Indigo was the original blue dye in Levi Strauss jeans. Indigo is often combined with henna to produce rich dark brown to black shades.

Horsetail, (Equisetum arvense L. ), Horsetail is nourishing and hydrating, stimulates blood vessels in the scalp and has been used for centuries as a hair growth herb. The silica in horsetail helps to keep hair strong and adds shine and lustre to hair.

Lemon balm, (Melissa officinalis L.). Lemon balm is a mild astringent, makes a very good rinse for those with oily hair. The toning properties of Lemon Balm help balance and refresh hair and scalp.

Lemongrass (Cymbopogon citratum Stapf.). Lemongrass has astringent and tonic properties that make it useful in the treatment of scalp inflammations. Lemongrass balances skin oil by helping to normalize oil production and is useful for both oily and dry hair.

Marsh Mallow (Althaea officinalis L.). Marsh Mallow soothes and provides relief from scalp irritation. A great alternative to store bought conditioners, it contains mucilage, which provides "slip" to help detangle thick naturally curly, wavy and Afro type hair. High in plant proteins, it nourishes conditions and promotes hair growth and lustre.

Mullein, (Verbascum thapsus L. ), Mullein rich in mucilage, has been used as a soothing emollient for inflammatory scalp conditions and dry hair and scalp. Mullein can be used as a floral rinse to add golden highlights and brighten hair.

Oat Straw (Avena sativa L.). Oat Straw has emollient qualities promotes softness, body, and shine. It contains nutrients that aid in healthy scalp maintenance and hair growth. Oat straw tea brings out highlights in blond hair.

Parsley (Petroselinum crispum (Mill.) Airy-Shaw ). Parsley moisturizes, gives lustre, stimulates growth, soothes scalp inflammation and helps with dandruff. Parsley is high in essential vitamins and antioxidants which are essential for protecting the hair and scalp from free radicals. It also enriches colour and gives a nice lustre to hair.

Peppermint (Mentha piperita L. ). Peppermint leaves are widely recognized for their anti-inflammatory, antibacterial and astringent properties. It stimulates nerve endings and increase local blood flow to the scalp and cools and refines the scalp. It not only moisturizes and soothes an irritated scalp, but also stimulates hair follicles. This herb is often used as an oil applied directly to the scalp, as an ingredient in hair products. According to a Toxicological Research study performed on the use of peppermint oil for hair growth, the results show that by the end of four weeks, 92% of patients showed hair growth.

Plantain (Plantago major L.). Plantain moisturizes the scalp and is one of the most effective anti-itching herbal remedies available. It is a good scalp stimulant and used in many hair loss treatments.

Red Clover (Trifolium pratense L. ). Red Clover a natural anti-inflammatory, has been used for centuries to help with many types of skin problems. It is one of the most useful remedies for children with eczema. It is also useful for the treatment of other chronic skin conditions such as psoriasis.

Rhubarb Root (Rheum rhaponticum L.). Rhubarb Root hair rinse will create rich, warm honey tones in blonde hair. It is sometimes used with henna to create reddish blonde tones.

Rose Petals & Rose Hips (Rosa spp). Rose Petals has healing properties that are useful in treating mild scalp inflammation, moisturizing and nourishing qualities that promote shine and stimulating properties that increase the blood supply in the scalp to promote hair growth. Rose petals also brighten red hair. Rose hips, packed with Vitamin C, strengthens the hair shaft and brightens red hair. 

Thyme (Thymus vulgaris L.). Thyme has antiseptic and antifungal properties that cleanse, heal and soothe the scalp. Thyme is often used in deep cleansing shampoos, helps ease dandruff and stimulates hair follicles to help with hair loss.

Watercress (Nasturtium officinale R.Br.). Watercress is mild acidic and contains lots of minerals like iron and phosphorus. It revitalizes oily hair, removes oil and soap residue and gets hair really clean. It has also been used  as an anti-hair loss treatment due to its high content of zinc and biotin.

Brinjaship /Yarrow (Achillea millefolium L. ). Brinjaship is effective for treating dandruff, itchiness, scalp irritation and oily scalp. It has also been shown to help counteract hair loss. Regular use of a strong yarrow tea will lighten hair.

Yucca Root (Yucca aloifolia L.). Yucca Root, an emollient that contains natural saponins, a natural cleansing and foaming agent, making it an ideal ingredient in shampoo and other hair care products. It is widely used as a remedy for hair loss or hair thinning. It is not a cure for baldness, but the root extracts will stimulate the scalp. The ingredient is most effective as a scalp treatment because it contains saponins, which are cleansers that also reduce inflammation, itchiness, and dandruff. It soothes and nourishes the scalp, prevent hair loss and cure dandruff.

This drug can be our answer for antimicrobial resistance

Antibiotic resistance is one of the man-made disasters and the “resistome” is a dynamic and mounting problem. Causes of the global resistome are overpopulation, enhanced global migration, increased use of antibiotics in clinics and animal production, selection pressure, poor sanitation, wildlife spread, and poor sewerage disposal system. Antibiotic treatment is one of the main approaches of modern medicine which is used to combat infections.

Why it is a Global Crisis??

  • Antibiotic resistance is a substantial economic burden to the whole world.
  • Antibiotic consumption worldwide increased 65% between 2000 and 2015 and doubled in lowand middle-income countries.
  • People still die because of lack of access to antibiotics than from resistant infections.
  • Unrestricted and inappropriate use of antibiotics will result in more infections that are untreatable, or more costly and difficult to treat.

WHO Guidelines to prevent Anti-Biotic Resistance:

  • Take antibiotics according to the prescription of your doctor.
  • Do not take more than prescribed anti-biotics and ensure complete Course.
  • Do not save antibiotics for the next illness, discard any leftover medication.
  • Do not ask for antibiotics when there is no need.

Natural way to combat anti-biotic Resistance:

Fifatrol a multidrug combination with power of five phytomineral active compounds and 8 herbal extracts having the potential to fight against bacterial infections and the resistant strains of various pathogens.

Fifatrol a natural antibiotic: A study

Testing Sample– Fifatrol Tablets and its individual classical components namely Tribhuvan kirti rasa, Sanjeevani vati, Mrityunjaya Ras, Sudarshan Ras

Study conducted at– Department of Microbiology, AIIMS Bhopal

Objective of the study

  1. Determination of antibiotic susceptibility pattern of various microorganisms against the Fifatrol (MDC).
  2. Determination of anti-microbial activity of Fifatrol against the various sensitive and resistant strains.
  3. Determination of Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) for antibiotics.
  4. In-vitro cytotoxic studies of the drug.

Bacterial Strains selected for study:

In this study four bacterial trains were taken of laboratory grade which includes Salmonella typhi, Staphylococcus aureus, Staphylococcus epidermis, Staphylococcus Saprophyticus except S.typhi which was clinically isolated for experimental estimation.

TABLE 1

MIC (The minimum dose required to inhibit the growth of pathogen) of FIFATROL TABLETS & various classical preparations against various pathogens.

 

BACTERIA

FIFATROL

SANJEEVANI

TRIBHUVAN KIRTI RAS

MRITYUNJAY RAS

Salmonella typhi

62.5 μg/ml

125 μg/ml

125 μg/ml

500 μg/ml

Staphylococcus aureus

125 μg/ml

500 μg/ml

0 μg/ml

0 μg/ml

Staphylococcus epidermis

125 μg/ml

31.3 μg/ml

7.81 μg/ml

7.81 μg/ml

Staphylococcus Saprophyticus

500 μg/ml

125 μg/ml

31.3 μg/ml

500 μg/ml

The study concludes:

Various classical preparations i.e. Tribhuvan kirti rasa, Sanjeevani vati, Mrityunjaya Ras showed inhibitory actions against selective pathogens where as fifatrol significantly inhibits the growth of all these pathogens mentioned above. Fifatrol inhibits the growth of various pathogens at different MIC dosage and remarkably inhibits the growth of S.typhi at lowest dose of 62.5 µg/ml.

Established Safety study:

Conducted at: Accuprec Research Labs Pvt. Ltd. Duration: 28 days

Dosage: 310 mg, 620 mg, 1240 mg/kg in wistar rats

Outcome: no abnormal findings from gross pathological examination of internal organs in all groups.

Formulation found to be safe at 310,620,1240 mg/kg when administered for 28 days.

Conclusion of the study:

  • Fifatrol is more susceptible to S.typhi, S.aureus, S.epidermis, S.saprophyticus at 1mg/ml concentration.
  • The study showed encouraging results with significant growth inhibitory effect present in fifatrol at lowest concentration of 62.5 µg/ml.
  • Fifatrol is effective against pathogens primarily causing upper respiratory tract infections enteric fever and sinusitis.

Note- Further investigation on enterobacteriaceae family i.e. E. coli, Enterococcus faecalis, P.mirabilis and other pathogens are still under ongoing clinical evaluation.

दिल्ली की जहरीली हवा से काली खांसी को रोक सकती है जूफा

गैस चैंबर बन चुकी दिल्ली में लोगों को काली खांसी हो रही है। अस्पतालों में भी खांसी के साथ ही कफ, बुखार इत्यादि लक्षणों के साथ मरीज पहुंच रहे हैं। ऐसे में इन मरीजों को जूफा औषधि काफी कारगर साबित हो सकती है। आयुर्वेद में एंटीवायरल को लेकर ऐसी तमाम औषधियों का जिक्र है जिनके सेवन से व्यक्ति पूरे परिवार की प्रदूषण से रक्षा कर सकता है।हिमाचल के लाहौल स्पीती पहाड़ी इलाके में मिलने वाली जूफा औषधि एंटीवायरल के रुप में काम करती है। डॉक्टरों की मानें तो जूफा के अलावा तुलसी, लौंग, वासा, पिपलि, गोजिहा, दालचीनी, कटेली, बहेडा, अंजीर, उनाब इत्यादि के मिश्रण का सेवन करने से खांसी और कफ से आराम मिल सकता है, जुफेक्स फोर्टे भी ले सकते है। इसमें ये सभी मिश्रण हैं, जिसका सेवन गुनगुने पानी के साथ किया जा सकता है।
 
प्रशांत विहार स्थित निगम के आयुर्वेद अस्पताल के चिकित्सा अधीक्षक डॉ. आरपी पाराशर बताते हैं कि जूफा, तुलसी, भृंगराज इत्यादि औषधि कफ को बाहर निकालने में मदद करती हैं। साथ ही इन औषधियों से रोग प्रतिरोधक क्षमता भी मजबूत होती है। इस समय दिल्ली के प्रदूषण से लोग एलर्जी के शिकार हो रहे हैं। इसमें खांसी, कफ, बुखार, सिरदर्द इत्यादि लक्षण आते हैं। 

अगर जल्द ही इनका उपचार नहीं किया तो ये संक्रमण में तब्दील हो सकती हैं। इसके अलावा कई तह वाल साफ कपड़ा नाक पर बांधकर बहुत बारीक कणों को शरीर में पहुंचने से रोका जा सकता है। कई तह होने से 2.5 माइक्रोन से छोटे कण भी शरीर में प्रवेश नहीं कर पाएंगे। जलनेति, स्वेदन, वाष्पीकरण के जरिए भी आराम हो सकता है। 

दूध या चाय में हल्दी, तुलसी, अदरक, लोंग, काली मिर्च उबालकर पीने से गले की खराश ठीक हो जाएगी और प्रदूषित कण भी शरीर से बाहर निकल जाएंगे। दूध में खजूर, छोटी पीपल, काली मिर्च और सौंठ उबालकर पीने से शरीर की इम्यूनिटी बढ़ेगी जिससे प्रदूषण जन्य रोगों से बचाव हो सकेगा।

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आयुर्वेदिक दवाओं से छिपा है किडनी की बीमारी का असरदार इलाज

कोलकात्ता में चल रहे भारत अंतर्राष्ट्रीय विज्ञान मेले में पहली बार आयुर्वेद दवाओं पर एक विशेष सत्र का आयोजन किया गया जिसमें गुर्दे के उपचार में इसके प्रभाव पर चर्चा की गई।

आयुर्वेद में किडनी (गुर्दे) की बीमारी का असरदार इलाज संभव है। आयुर्वेद की दवा गुर्दे को नुकसान पहुंचाने वाले घातक तत्वों को भी बेअसर करती है। कोलकात्ता में चल रहे भारत अंतर्राष्ट्रीय विज्ञान मेले में पहली बार आयुर्वेद दवाओं पर एक विशेष सत्र का आयोजन किया गया जिसमें गुर्दे के उपचार में इसके प्रभाव पर चर्चा की गई।

इस सत्र के दौरान एमिल फार्मास्युटिकल के कार्यकारी निदेशक संचित शर्मा ने आयुर्वेद के उपचार में प्रभावी दवा नीरी केएफटी के बारे में अब तक हुए शोधों का ब्यौरा पेश करते हुए कहा कि नीरी केएफटी गुर्दे में टीएनएफ अल्फा के स्तर को नियंत्रित करती है। टीनएफ एल्फा परीक्षण से ही गुर्दे में हो रही गड़बड़ियों का पता चलता है तथा यह सूजन आदि की स्थिति को भी दर्शाता है। टीएनएफ अल्फा सेल सिग्नलिंग प्रोटीन है।

शर्मा ने अपने प्रजेंटेशन में कहा कि नीरी केएफटी को लेकर अमेरिकन जर्नल ऑफ फार्मास्युटिकल रिसर्च में शोध प्रकाशित हो चुका है। इस शोध में पाया गया कि जिन समूहों को नियमित रूप से नीरी केएफटी दवा दी जा रही थी उनके गुर्दे सही तरीके से कार्य कर रहे थे। उनमें भारी तत्वों, मैटाबोलिक बाई प्रोडक्ट जैसे क्रिएटिनिन, यूरिया, प्रोटीन आदि की मात्रा नियंत्रित पाई गई। जिस समूह को दवा नहीं दी गई, उनमें इन तत्वों का प्रतिशत बेहद ऊंचा था। यह पांच बूटियों पुनर्नवा, गोखरू, वरुण, पत्थरपूरा तथा पाषाणभेद से तैयार की गई है।

उन्होंने कहा कि जिन लोगों के गुर्दे खराब हो चुके हैं लेकिन अभी डायलिसिस पर नहीं हैं, उन्हें इसके सेवन से लाभ मिलता है। उन्हें डायलिसिस पर जाने की नौबत नहीं आती है।

उन्होंने यह भी कहा कि आयुर्वेद में कई उपयोगी दवाएं हैं। आयुर्वेद में उन बीमारियों का उपचार है जिनका एलोपैथी में नहीं है। लेकिन उन्हें आधुनिक चिकित्सा की कसौटी पर परखे जाने और प्रमाणित किये जाने की जरूरत है। इस दिशा में डीआरडीओ और सीएसआईआर ने कार्य किया है इस पर और ध्यान दिये जाने की जरूरत है।

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किडनी की बीमारी से है परेशान तो आयुर्वेद का ये नुस्खा करेगा ठीक

कोलकाता में चल रहे भारत अंतरराष्ट्रीय विज्ञान मेले में किडनी की बीमारियों के उपचार को लेकर आयुर्वेद का प्रभावी शोध सामने आया है. इसमें पता लगा है कि आयुर्वेद की जड़ी-बूटियों में इंसान के किडनी के उपचार और उन्हें स्वस्थ रखने की बहुत क्षमता है, लेकिन अब तक इन दवाओं का बड़े पैमाने पर इस्तेमाल नहीं किया गया है.

हालांकि, अब इस दिशा में सुगबुगाहट शुरू हो गई है. आधुनिक चिकित्सा विज्ञान भी इन पैथियों में दिलचस्पी ले रहा है. आयुर्वेद दवाओं पर एक विशेष सत्र में एमिल फार्मास्युटिकल के कार्यकारी निदेशक संचित शर्मा ने बताया कि आयुर्वेद के उपचार में प्रभावी दवा नीरी केएफटी दवा किडनी को नुकसान पहुंचाने वाले घातक तत्वों को भी बेअसर करती है.

शर्मा ने अपने प्रजेंटेशन में कहा कि नीरी केएफटी किडनी में टीएनएफ अल्फा के स्तर को नियंत्रित करती है. टीनएफ एल्फा परीक्षण से ही किडनी में हो रही गड़बड़ियों का पता चलता है. साथ ही यह सूजन आदि की स्थिति को भी दर्शाता है. बता दें कि टीएनएफ अल्फा सेल सिग्नलिंग प्रोटीन है.

संचित शर्मा ने आगे बताया कि नीरी केएफटी को लेकर अमेरिकन जर्नल ऑफ फार्मास्युटिकल रिसर्च में शोध प्रकाशित हो चुका है. इस शोध में पाया गया कि जिन समूहों को नियमित रूप से नीरी केएफटी दवा दी जा रही थी उनके किडनी सही तरीके से कार्य कर रहे थे. उनमें भारी तत्वों, मैटाबोलिक बाई प्रोडक्ट जैसे क्रिएटिनिन, यूरिया, प्रोटीन आदि की मात्रा नियंत्रित पाई गई.

वहीं, जिस समूह को दवा नहीं दी गई, उनमें इन तत्वों का प्रतिशत बेहद ऊंचा था. यह पांच बूटियों पुनर्नवा, गोखरू, वरुण, पत्थरपूरा तथा पाषाणभेद से तैयार की गई है.
मालूम हो कि किसी भी तरह के दर्द को लेकर पेन किलर जैसी दवाएं लोग ले रहे हैं. जिसका असर उनकी किडनी पर हो रहा है. देखा गया है कि दवाओं के कारण किडनी की कार्यप्रणाली में गिरावट आ रही है, उन लोगों में आयुर्वेद का यह फार्मूला कारगर हो सकता है क्योंकि यह दवाओं से होने वाले दुष्प्रभाव के साथ-साथ अन्य दूषित तत्वों को भी नियंत्रित करता है. यह भी देखा गया है कि जिन लोगों की किडनी खराब हो चुकी है लेकिन अभी डायलिसिस पर नहीं हैं, उन्हें भी इसके सेवन से लाभ मिलता है.

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The new way to assess and manage pre-diabetes

This world diabetes day on November, 14th let’s discuss the new paradigm of assessment and management of pre-diabetes. The article opens a new world where it discusses an effective and economic tool to calculate the risk of type-2 diabetes along with its effective management.

Diabetes mellitus has become synonymous with the name of our country. And it seems true in the sense that India has highest number of diabetics in the entire world. The recent projections show that 98 million Indians will be plagued with this silent killer, rising 41.6 percent from 69.2 million in 2015. The more grave concern is the count of people waiting to be veiled in the dark fabric of diabetes. Yes, the percentage of pre-diabetics percentage is alarmingly high, close to 16% with urban population at the maximum risk.

Signal to start

With World Diabetes day around the corner and its theme of Test2Prevent serves as good signal to start our campaign against pre-diabetes. This campaign holds a greater meaning for us as the International Diabetes Federation (IDF) claims that 1 of every 2 cases of type-2 diabetes is totally preventable, this means that if we can stop a patient from sliding into type-2 diabetes then by 2030 India might not remain the diabetic capital of the world which itself would be a great achievement compared to today’s scenario.

Simplifying screening of pre-diabetics

In a country like India, with humongous population and stressed economic conditions screening of patients for pre-diabetics become an unsurmountable task. The IDF has come up with an effective tool to assess the risk factor of type-2 diabetes mellitus, the tool known as Finnish diabetes risk score (FINDRISC) is simple, practical and inexpensive way to quickly identify people who may be at a higher risk of type 2 diabetes and who need to have their level of risk further investigated. FINDRISC was developed by and designed by Adj. Prof Jaana Lindstrom and Prof. Jaakko Tuomilehto from the National Institute for Health and Welfare, Helsinki, Finland.

FINDRISC contains a set of eight scored question which gives a totalled score at the end depending on the answer of the respondents. The scored is then interpreted by matching the score with the range of very low to very high.

American diabetes association also endorses the usage of FINDRISC as simple, fast, inexpensive, non-invasive, and reliable tool to identify individuals at high risk for type 2 diabetes.

You can also click the link to find FINDRISC score

check FINDRISC score

Handling Antibiotic Resistance with Ayurveda

Discovery of antibiotics has served as the cornerstone of modern science since ages, but however due to persistence overuse or misuse of antibiotics in humans have encouraged the emergency to fix the solution of the antibiotic resistance, which occurs when microbes such as bacteria become resistant to drugs used to treat them. 

Antibiotic: From life savior to life threat

Although earlier antibiotics are found to be responsible for the eradication of infectious diseases in reality due to continuous growing use of them, emerging & re-emerging infectious diseases have evolved so tremendously.

Today “The medicine discovered to eradicate them are facing tough defeat in the battleground” and therefore antimicrobial resistance (AMR) has emerged as a major global threat, especially in India where according to the Indian Network for Surveillance of Antimicrobial Resistance, there are 41% of resistant Staphylococcus aureus while multi-resistant entero-bacteriaceae is also very high.

Few studies have also reported resistance to Salmonella typhi to various multi-drug combinations.

Facts that cause resistance

  • Self-consumption of antibiotics
  • Over-prescription of antibiotics
  • Patient not finishing the entire antibiotic course
  • Use of antibiotics in viral infections such as common cold
  • Absence of better solutions

Need more than new antibiotic to fight resistance

Ayurveda’s approach is unique, natural and gentle that considers microorganisms as symbiotic parts of the entire ecosystem avoiding wars or conflicts resulting in a focus on strengthening immunity.

Therefore in the battleground where bacteria are immune to most of the antibiotics, the complex active phytochemicals present in various herbal & classical preparations does not let the bacteria to develop resistance.

Way ahead with Fifatrol

Since the rich heritage of knowledge of various herbs such as Tulsi (Ocimum sanctum), Giloe (Tinospora cordifolia) are already mentioned in ancient texts but with the recent study conducted on FIFATROL, AIIMS Bhopal illustrate power of various classical preparation such as Sanjeevani Vati, Tribhuvan Kirti ras, mrityunjay ras & other herbs otherwise use in fever, cold, body aches have shown potentially effective as a NATURAL ANTIBIOTIC, as fifatrol significantly inhibits the growth of various pathogens especially on Staphylococcus Spp. & Salmonella typhi bacteria  primarily causing URTI & typhoid, aiming towards providing a structured solution

Fifatrol an herbal product by Aimil Pharmaceuticals is a multi-drug combination which not only works as natural anti-microbial, anti-infective but also efficiently built immunity in order to prevent further manifestation.

In the era where the untoward effect of antibiotics is a major concern globally, fifatrol, on the other hand, shows no toxicity hence offering completely wellbeing.

The World Health Organization is taking important steps in order to create awareness about antibiotic resistance and eradicate the issue from the grassroots level before it turns into an epidemic. These efforts include organizing awareness weeks at different country-level and state-level organizations to help the common individuals understand the side effects and problems related to antibiotic resistance.

In addition to the above, Aimil Pharmaceuticals has committed itself, hand in hand with WHO’s goal and contributing at the peak to the efforts in eradicating antibiotic resistance.

Our global contribution to 2019 “ANTIBIOTIC AWARENESS WEEK”

  • Pledge for a resistant free nation 
  • Use of antibiotics only in emergency conditions
  • Do not take, share or use leftover antibiotics
  • Spread awareness about antibiotic resistance  
  • Follow proper sanitization 
  • Benefiting with an herbal solution
  • Use of “NATURAL ANTIBIOTIC” fifatrol

    “Think Twice, Seek Advice or Pay the Price”

Natural Regime for Healthy Skin

Skin being the largest organ of the body and first line of defense from harmful microorganisms, it’s important to take good care of it. However, people don’t understand the criticality of healthy skin. Although modern science has proved the correlation among Gut-Brain-Skin axis, in which Acne is a common disorder. It is frequently associated with depression, anxiety and other psychological sequelae, due to which endotoxins are released in body. Let us know more about gut and skin correlation.

Gut & Skin correlation

Gut and skin works in hand in gloves situation. When psychological distress alone or in combination with high fat diet, processed comfort foods devoid of fiber, cause alterations to gut motility and microbiota profile. Loss of normal microbial biofilm (Bifidobacterium in particular) causes intestinal permeability and endotoxins secretion. This cascade increases the likelihood of excess sebum production, exacerbations in acne and additional psychological distress.

The best prevention strategy against the harmful effects of Gut-Brain-skin axis is a well regulated lifestyle (caloric restriction, body care and physical exercise for body), with low stress conditions and a balanced nutritional diet, including anti-oxidative rich food.

Eating

Nutrition is important for health. An unhealthy diet can damage your metabolism. Having the correct balance of food will feed the skin vital nutrients which is needed to help it stay soft, supple and blemish-free. 

Exercising

Exercise helps nourish skin cells and keep them vital by increasing blood flow exercise helps flush cellular debris out of the system, Blood carries oxygen and nutrients to working cells throughout the body, including the skin,

Sleep

Daily metabolism perpetuates the decline and rejuvenation of cellular tissue and the body’s self-repair takes place when you are asleep. Seven to nine hours of night sleep daily is considered an optimum for most individuals for a healthy lifestyle.

Reducing Stress

Your body responds to everyday stress with a release of hormones that prepares you to react. Although some stress is inevitable and necessary, excess can lead to various health problems. If you don’t relieve this excessively stressful state through relaxation, the effects build and can create muscular pain, headaches, sleep disturbances, Acne and other symptoms. A lifestyle that includes regular stress management, breaks this cycle before it can progress to unhealthy levels. You can achieve physical relaxation through stretching, body massage, yoga or enjoyable exercise. Connect with friends and family to relieve mental pressures and take time out to read, pursue a hobby or experience another activity that makes you feel good.

Ayurveda

In India, records of Ayurvedic medicine date back to about 3000 BC. The system of Ayurvedic medicine combines physiological and holistic principles. It is based on the concept that the human body consists of five energy elements that also make up the universe: (1) earth, (2) water, (3) fire, (4) air, and (5) space. The interactions of these five elements give rise to the three doshas (forces), seven dhatus (tissues), and three malas (waste products). All diseases are attributed to an imbalance among the three doshas

Ayurveda’s solution for diseased skin

A promising strategy for enhancing skin protection from oxidative stress is to support the endogenous antioxidant system, with antioxidants containing products Fruit, vegetables and herbal medicine consumption may represent the healthiest and safe method in order to maintain a balanced diet and youthful appearing skin. Purodil dual therapy provides poly herbal regimen, recommended for comprehensive management of acne and pimples. With unique benefits of dual therapy, it constantly treats all stages of acne, repairs acne damaged skin, helps to heal breakouts by detoxifying the impurities. It’s a rich source of phyto–constituents, alpha mangostin which locally inhibits 5-α reductase, reducess DHT level, reduces excessive sebum or oil secretion, eventually reduces the formation and recurrence of acne and pimples. Purodil works at a root cause level & gives fast relief.

Information on this website is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professionals. This website is meant for use by Indian residents only.