Author: Aimil

An epidemic of diabetes threatens the health of a large number of individuals worldwide. A pre-diabetes condition does not necessarily develop into diabetes if controlled well. Progression to diabetes can be prevented by lifestyle interventions and pharmacotherapeutic modes.

Warning: Obesity a major predisposing factor for diabetes

• One fifth of world's population will be obese by 2025, experts warn.
• New analysis of BMI trends found that from 1975 to 2014, the number of adults in the world classified as obese rose from 105 million to 641 million.
• The average person had become 1.5kg (3.3 pounds) heavier with each passing decade.
• If this trend continues, scientists predict 18% of men and 21% of women worldwide will be obese by the year 2025.

The review, published in The Lancet medical journal, also suggests more than 6% of men and 9% of women will be "severely obese" and putting their health at risk by 2025.

Diabetic Prevalence

The epidemic of pre-diabetes is likely to compound the existing diabetes crisis as many individuals with impaired glucose tolerance (IGT) will develop type 2 diabetes mellitus (T2DM) in the future. It is estimated that approximately 316 million people worldwide are with impaired glucose tolerance (IGT) and this is predicted to rise to 471 million by 2035.

According to the estimates of International Diabetes Federation (IDF) in 2013, India alone has 65.1 million people living with diabetes; this places India second to China.

Need

Type 2 diabetes is a global health challenge and the WHO has recommended research and use of complementary medicines for the management of this disease. Type 2 diabetes was previously considered as maturity-onset diabetes but, due to increasing rate of OBESITY, there is an increasing risk of developing this disease in childhood.

Goal

The goal of treatment is to maintain normal levels of blood glucose and prevent the development of complications.

Options available:

Dietary supplements – modulates glucose homeostasis and potentially improves lipid parameters, a desirable feature.

Numerous allopathic molecules available but none at par to manage condition safely in long term.

Plants provide an excellent source of drugs and a large proportion of currently-available drugs have been either derived directly or indirectly from plant sources. Herbs are reported to possess anti-diabetic activity.

An effective strategy to restrict global impacts of T2DM is by limiting the number of pre-diabetics.

Trigonella foenum graecum (Methi)

Obesity is one of the major risk factor for morbidity and mortality. Supplementing fenugreek seed extract helpful in reducing the body and adipose tissue weight. The probable mechanism of fenugreek decreasing the total body and adipose tissue weight may be that

1) Fenugreek flushes out the carbohydrates from the body before they enter the blood stream resulting in weight loss

2) Fenugreek seeds contain a high proportion (40%) of soluble fibre. This fibre forms a gelatinous structure (similar to gaur gum) which may have effects on slowing the digestion and absorption of food (carbohydrates & fat) from the intestine and create a sense of fullness in the abdomen, thus suppresses appetite and promotes weight loss.

In conclusion this plant is effective in managing blood lipids and sugar level and antioxidant activity of fenugreek providing protection to organs and inhibition of entrance diseases to body, too decrease body fats and is effective on obesity.

Pre-diabetic/ borderline diabetic advised to do lifestyle modification along with an herbal, safe and effective formulation BGR-34, a very promising formulation to control glycaemic parameters in pre-diabetic/ borderline diabetics in addition it improves quality life of patients due to optimize composition of vital herbs having scientifically proven and clinically tested anti-diabetic effects.

Fibromyalgia is complex syndrome marked by severe muscle pain accompanied by Fatigue, Morning stiffness, sleep disturbances & depression, and low grade fever, premenstrual & menstrual difficulties.

Hallmark of disease– Affects set of nine, “Tender Points”

• Back
• Buttocks
• Elbows
• Knees
• Neck
• Thighs

Fact

• Women’s get affected more than men’s.
• Fibromyalgia causes sleep disturbances

Age

Affects mostly between 20- 50 years

Symptoms

Appears gradually & generally worsen with time

Cause

No definite cause known

Beneficial herbs

Herb Name	Action
Boswellia serrate (Salai guggul), Pluchea lanceolata (Rasna), Zingiber officinale (Sunthi) and Curcuma longa (Haridra)	Eases Morning stiffness & joint pain Inhibits synthesis of prostaglandins
Piper longum (Pippli)	NSAID’s like activity without risk of bleeding or stomach upset
Valeriana wallichii (Tagar)	Muscle relaxant & induce  restful sleep
Vitex negundo (Nirgundi) , Withania somnifera (Ashwagandha)	Quenches free radicals

 

Consideration:

• Include Pomegranate in your diet. It has anti-inflammatory and anti-oxidant activity
• Drink plenty of fluid to help flush out toxins
• Be sure to get thyroid function test. Hypothyroidism causes set of similar symptoms.

Fibromyalgia is notorious and hard to treat but gracility of Ayurveda has solved the issue with goodness of herbs. Muscalt forte a comprehensive formulation available in market to save the suffering. For more easier and convenient option Muscalt forte is now available in syrup and spray forms also along with conventional tablet dosage form.  

Aimil Pharmaceuticals (I) Ltd. financially assisted in fulfilling the dream of one’s own clinic

A first ever Rashtiya Ayurved Yuva Mahotsav (RAYM) was organised at NIA, Jaipur by Ministry of AYUSH and NASYA from 14th – 16th September, 2017. The event witnessed huge footfall of young students of Ayurveda, Faculty members and delegates. The three day event comprised of various competitions pertaining to Art and culture.

Amongst all the ‘Discover the Doctor in You’ event grabbed the maximum attention where Dr. Niyas Meeran, a renowned motivational speaker conducted a skill development programme for students. Aimil Pharmaceuticals (I) Ltd. sponsored this programme and after the session a national level scholarship test was conducted and financial assistance of Rupees 1 lakh, 51000 and 31000 was awarded to 1st, 2nd and 3rd position holder to set up their own clinic.

Mr. Sanchit Sharma, Executive director of Aimil Pharmaceuticals (I) Ltd. after the event said “Aimil has always vouched for inclusion of Ayurveda into mainstream and we believe initiatives like these will go a long way in making the society healthy, Aimil will continue to support and organise various skill development programmes in the benefit of the students.”

A natural way to bypass opioid analgesics & NSAIDS to help you walk with ease, free of joint pain & healthy GIT.

If one feels pain and stiffness in joints or have swelling around them or trouble in moving around. Then it might be an indication towards – ‘Arthirtis’.

The world is witnessing an emergence in arthritis patients, suffering with disease as well as the inadequacy in available treatment. Not all patients achieve sufficient clinical response resulting in a need to switch to a new therapy regime to control disease. Furthermore, this therapeutic cycling that undoubtedly helping patients to live active & productive lives, sometimes contributes to progression of disease & irreversible structural joint damage, rendering yet painful condition.

CAM (Complimentary Adjuvant Therapy) hold promising hope for disease management

Subsequently, special diets, vitamins & other complimentary therapies are reported to help people in reducing disease progression & symptoms without causing possible untoward effects like GIT irritation.

In 2015, A significant clinical study published in ‘Indian Journal of Medical Research’, proving the efficacy of herb ‘Ashwagandha’, was conducted at premier medical institute AIIMS Delhi that validates the claims of ayurvedic texts about the herb Ashwagandha that its usage provides relief in tender, swollen joints and increased mobility in arthritis patients.

An exclusive proprietary product Muscalt Forte not only contains Ashwagandha but also contains herbs with alike properties viz. Haridra, Nirgundi and Salai Guggal that are scientifically validated for their anti-inflammatory, anti-oxidant, chondrio-protective & immuno-modulatory properties. Which makes the product a potential ayurvedic drug that will help not only in achieving primary goal of arthritis treatment i.e. controlling inflammation & pain like DMARDS, also it helps prevent the flare up of disease & its progression in long term treatment.

Diabetic Retinopathy (DR) is a perfect precedent to gauge the extent of damage that diabetes can inflict. A new research indicates on how a preventive drug can help us in shedding our blindfold.

With a diabetic being twenty-five times more likely to go blind than someone without diabetes, it's high time that we illuminate this path.

Tinospora cordifolia: A torch in the dark

A recent study published in Food and Chemical Toxicology discusses the prevention and management of DR in experimental subjects. The journal also discusses the molecular mechanism of action and presents the following points:

• Prevention against cataract development.
• Decrease in angiogenic markers such as VGEF (Vascular endothelial growth factor) and PKC (Protein Kinase C) in diabetic retina.
• Protection of pancreatic islet structure.
• Prevention of retinal oxidative stress
• Anti-hyperglycemic effect
• Reduction of TNF-ALPHA (Tumour Necrosis Factor) and IL-1 (Interleukin 1) BETA level

Tinospora cordifolia in a nutshell reduces blood glucose and inhibits over expression of angiogenic and inflammatory mediators which are distinct markers of DR.

Tinospora cordifolia with Berberis aristata, Pterocarpus marsupium, Gymnema sylvestre, Rubia cordifolia, Trigonella foenum-graceum are key ingredients of BGR-34 which has been developed by Council of Scientific and Industrial Research (CSIR) for an effective management of diabetes. With new researches pouring in, BGR-34 along with the management of disease is also gaining credibility for the prevention of triopathic complications associated with diabetes.

The drug was launched for commercial and marketing purposes by a Council of Scientific and Industrial Research (CSIR) lab in Lucknow on Sunday.

Lucknow: An anti-diabetes herbal drug, which is a scientifically validated, has been developed by Indian researchers to help treat and manage type-II diabetes mellitus.

As per a Times of India report, the drug named 'BGR-34' was launched for commercial and marketing purposes by a Council of Scientific and Industrial Research (CSIR) lab in Lucknow on Sunday. Jointly developed by two CSIR laboratories, National Botanical Research Institute (NBRI) and Central Institute for Medicinal and Aromatic Plant (CIMAP), the drug has no side effect and is based on Ayurveda.

During clinical trials, the drug has been found to be safe and effective on animals, showing 67% success. The drug will help maintain normal blood glucose levels, reduce chances of complications due to persistent high blood glucose levels and impart a good quality life to patients with high blood sugar levels, the report added.

The drug may cost Rs 500 for 100 tablets and will be available in the form of tablets.

News Source : http://zeenews.india.com/news/health/health-news/scientifically-proven-anti-diabetes-herbal-drug-launched-in-india_1814530.html